Construction of a crown ether-like supramolecular library by conjugation of genetically-encoded peptide linkers displayed on bacteriophage T7.
نویسندگان
چکیده
By using the 10BASEd-T, we have synthesized a crown ether-like macrocyclic library possessing randomized peptide linkers on bacteriophage T7. Among 1.5 × 10(9) diversities of the supramolecule candidates, we have obtained a specific binder for the N-terminal domain of Hsp90.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 30 شماره
صفحات -
تاریخ انتشار 2014